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1.
If you buy 40 dollars worth of crack for 20 dollars and sell it for 40 dollars you just pulled a double up.
Ay main let me get a double up up off you.
by Acebee Racine,WI September 24, 2003
 
2.
Strap on another condom
just in case the condom snap
by Lehem October 18, 2003
 
3.
Run, Take off, Speed away. Break out.
"Double-up, the Elroy comin'."
by Tha Bean December 03, 2003
 
4.
To do a threesome; menage-a-trois; 3P
If you ever got two chicks both with dizzy legs bring 'em both and do a double up on 'em, dawg!

Kiss me; now kiss her; we do the double up like that!
by westsan July 28, 2009
 
5.
To ready or prepare oneself
"Double up fool! It's the 5-0!"
by S-Dada October 02, 2006
 
6.
To put two people on something, i.e. double team

To double something, i.e. drugs
1) AY YO DOUBLE UP ON T MAC HES KILLIN US
2) Yo double me up on this weed here
by pwnz0r September 19, 2003
 
7.
In sleepovers, it's the act of having to sleep next to someone of the same gender in the same bed.

The term doubling up is commonly used to make the one using the word seem less of a homosexual, as saying "Let's sleep togeether." Can spur awkwardness.
We need to double up, tonight. Just make sure we don't look eachother in the eyes.
by Bill  June 12, 2011