When you take a dook that utterly destroys the inside of your toilet and leaves the inside of the bathroom and the surrounding 25 ft of the bathroom smelling like sin.
Dude, stay outta the bathroom! Andrew just dook nuked it up again!
by Mephibosheth1 July 15, 2011
1 more definition
when you take a huge shit with a nuclear force who's smell permeates the entire edifice for hours.
I just fucking dooknuked like it was the bombing of 1945.
by horse man August 31, 2007