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1.
1) used when a friend is having a tough time or seems to have a lot on their plate to make them laugh off their stress and to show them that you know they can do it.

2) a phrase that closely resembles the usage of don't die and the meaning of man up or buck up

3) used less for mocking and more for inspiration/consolation
Friend A: "I can't believe I have an 8-10 page paper, two tests, and a 10 minute presentation all in one week."
Friend B: "Don't cry."
Friend A: "Thanks man, your tender words will help get me through it."
by Dr. Sassafrass April 13, 2010