When something is numptified, it has gone wrong, generally in a silly or just plain pointless way. Also it can be used to describe somebody's brain function, especially due to lack of sleep.
"damn it, the cake's gone numptified - it hasn't risen at all"
"Sorry if I'm not making sense, I've gone numptified since last night's party"
"That numptified checkout girl couldn't find the bar-code on the back of my book. It was totally visible though!"