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1.
To fiddle or play about with the settings or configuration of something.
I diffled with my PC the other night
by LordOfKaos January 14, 2008
 
2.
A dick in front of an eagle
joe:HEY YOU SEE THAT DIFFLE????!!!
john:WHOA ITS FLYING SO HIGH WITH THOSE DICKS
by cutty1234 June 08, 2009