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1.
derogotory stament of pain wished apon an ex girlfriend
girl: you have a small cock!
dude; die bitch
by NATAS666 September 12, 2006
 
2.
"DIE BITCHES" is used to break an awkward silence.
From explosm.net's 1184 comic where a naked guy wants to kill crickets that only chirp at awkward moments. He yells "DIE BITCHES!!" and fires a shotgun blast at the crickets when they chirped.
<Haclon> So?
<Danny34> soo....I'm gay everyone
<Haclon> o_o
<XIF> DIE BITCHES!
by Stephen Ratkovich April 12, 2008