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1.
"A drug with properties and effects similar to a known hallucinogen or narcotic but having a slightly altered chemical structure, especially such a drug created in order to evade restrictions against illegal substances."
(Answers.com)
A synthetic chemical (Often produced by a high-tech lab) the purpose of which is to produce a reliable state of intoxication (As opposed to plant-based inebrients, whos effects may vary greatly from one individual to another)
Ecstacy (MDMA), BZ (A "superhallucinogen" concocted by the CIA), CC3P, Methamphetamine, MPPP.
by je'kir August 09, 2005
 
2.
Pills such as ecstasy
I got some amazing Red Gucci designer drugs last night.

(Red Guccis=type of E)
by Slow_Motion December 29, 2008