Top Definition
to dislike extremely with no reason or foundation; seemingly similar to unfounded prejudice or stupidity
I have just met you, but derpise you.

Katherine and Alyssa derpise Skype for no apparent reason, except that they think it is annoying.
by HerParties May 16, 2011

Free Daily Email

Type your email address below to get our free Urban Word of the Day every morning!

Emails are sent from We'll never spam you.