self explanatory. when you derp so much that it has become an addiction. soon after you become a derpaholic, you will most likely contract derpes, whether you give it to yourself from derping too much or a derpes positive person will give it to you.
Michael: "Derp derp derp derp derp derp!!!" Brandon: "Get away from me you derpaholic psychopath!" Michael: "Embrace the derp!!"