To have a retarded face, or expression causing others to find it funny, creepy or just plain stupid.
Ex. 1 Jennifer Lawrence is the queen of derp because of the faces she makes.

Ex. 2 "I'm bored."
"Me too."
*Awkward silence.*
"Derp."
"Yeah..."

Ex. 3 Jennifer Lawrence Queen of Derp trended on Twitter worldwide. (FACT)
by Swim-on-and-on-and-on.... September 07, 2012

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Universal word that can mean anything.
"That was derping awesome"

"Teach me how to derp, teach me-teach me how to derp"

"Go derp yourself you derping piece of derp!"

"Derp you!!"
by JvMarsh November 20, 2011

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From the Online multi-player game, World of Tanks, it refers to the biggest and most explosive slowly reloading gun that one can have for a particular tank.
Hey, do you have derp on that KV tank? No, I have the stock gun. Noob.
by SiemaUSA October 15, 2011

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An incurable disease, at least until the introduction of Duck Sauce's "Barbra Streisand" with a combination of yelling "Unf Unf Unf" between two mirrors.
Kindoflike Bloody Mary three times, but this one actually works. 50% of the time.

It is known to afflict a certain Jason Liu's face constantly (See "Jason Liu" for more information)

Commonly associated with "Herp"
DocMo: "Hi what's your name?"
Jason: "Derp"
DocMo: "Barbra Streisand"
Kenja: "UNFUNFUNF"
by kendaninjabinja May 02, 2011

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a totally ridiculous person who abbreviates all their words and says that they have a ghat. popular sayings are nahnahnahnah and wanna die? Derps tend to live in basking ridge. subjects often say wheres ma ghat? they will also ask for qual rides to chip after prac whichs translates to quality ride to chipotle after practice. a list of common abbreviations are garb = garbage, ridic= ridiculous, imposs= impossible, ment= mental
Ridge Hockey Team, Derp Dan
by nyjets28 January 19, 2011

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10. Something obvious.
Person #1: What?

Person #2: I love you, that's what. Derp! :P
by Inaia December 18, 2010

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The state of being cross-eyed and generally looking stupid, possibly with some showing of teeth for effect. Being derp can be voluntary or involuntary
You would be derp if you lost your retainer, were perplexed by something etc.
by Daraghderp November 13, 2010

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N. 1.Epic fail. An attempt at something of extreme greatness, but an utter fail. Antonym: Herp. 2. An expression used in the act of failing, often an exclamation. 3. The name for someone/thing that has failed.

V. Sucking really hard.
N. 1.
1: That guy ate it so hard on that triple pirouette.

2: I know, right?! What a derp.

N. 2.
1(while belly-flopping into a pool): DERP!

N. 3.
1: You honestly tried to pull off cooking 30 brownies in 20 minutes? You fucking derp.

V.
1: Have you ever herped so hard you derped?
by RadioactivePuppy October 26, 2010

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