To have a retarded face, or expression causing others to find it funny, creepy or just plain stupid.
Ex. 1 Jennifer Lawrence is the queen of derp because of the faces she makes.

Ex. 2 "I'm bored."
"Me too."
*Awkward silence.*
"Derp."
"Yeah..."

Ex. 3 Jennifer Lawrence Queen of Derp trended on Twitter worldwide. (FACT)
by Swim-on-and-on-and-on.... September 07, 2012

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derp-Interjection

Used when replying to a previous statement that is either 1)irrelevant, 2)unintelligible or 3)pointless.
1) following a conversation that had revolved around riced out cars, Jim adds:
"Does anyone else think that corn dogs looks like rats having sex?"
-DERP!

Jim after smoking weed:

"I woke up, or was I already awake? It doesn't matter because THE CAT WAS STILL sleeping!!! ISN'T that odd?
-DERP

3)The sun hurts eyes!
-DERP!
by DFreshalot September 28, 2011

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From South Park. Originally meant to be said when someone does or says something dumb. Now, said by douchebags and trolls for any reason whatsoever...or sometimes none at all.
John F Kennedy: "Do not pray for easy lives. Pray to be stronger men."

Lindon B Johnson: "Derp."
by GIVEmEEEEEEEEthePower June 11, 2011

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The action of pure randomness and retardation.
Guy 1: My entire family just died!!!!
Guy 2:..........derp!
by itzadolfin!! May 10, 2011

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Symbolizing a retarded face, look, etc., making fun of it.
Im the Joker, Batman! DERP!
by BATMAN DERP February 06, 2011

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Sound simultaneously expressing supreme dorkiness and excitement of boston terriers.
derp, derp, derp (repeat until satisfied)
by BT Supreme January 20, 2011

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a stupid person, or action
"Danny, your being a huge derp right now.
by MrSexy282 May 21, 2010

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Describes a person who usually adds retarted remarks or statements to a conversation. The speaker is usually mocked and teased afterwards and sometimes forced to wear a DERP HAT and told they are full of Derp or the derp is strong with them
A person spots the obvious during a conversation, everybody then says to the person HURR DERPA, HERPA DERPA HERPA HURR. HERPY DERPY HURR.
by DERPA Herpa April 30, 2009

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