To have a retarded face, or expression causing others to find it funny, creepy or just plain stupid.
Ex. 1 Jennifer Lawrence is the queen of derp because of the faces she makes.

Ex. 2 "I'm bored."
"Me too."
*Awkward silence.*
"Derp."
"Yeah..."

Ex. 3 Jennifer Lawrence Queen of Derp trended on Twitter worldwide. (FACT)
by Swim-on-and-on-and-on.... September 07, 2012
Exclamation used during shitty situations.

"derp" is not yelled, but simply said.

Used instead of yelling "FUCK" or "GOD DAMMIT".

Shockingly, "derp" releases stress, anger, and sadness better than yelling and cursing.

Opposite of merp.
Imagine this. Getting lost during a road trip. You become extremely hungry. For whatever reason, you have a strong craving for Chick-fil-A, and refuse to stop anywhere else. You set your TomTom to the nearest Chick-fil-A, but is on his period and sends you to mother fucking Disney World instead. When you finally find a fucking Chick-fil-A, it's closed and you remember that it's Sunday.

"derp"
by ShredGnarShark July 06, 2012
Someone who thinks that the joke:
"Why did the witch ride her broom?"
"Because her vaccuum was too heavy!"

is worth laughing about.
That Linda is such a derp for laughing at that joke.
by Courtney_Elizabeth2013 January 29, 2012
See also herp:

Derp is a word that can replace anything in a sentence. It is somewhat of an everyword, such as fuck. Derp is most commonly used in le rage comics.
"Yo Derphina"
"Lets go to the herp n Derp"
"you look so derpy"
by Zombies<3 October 23, 2011
From the Online multi-player game, World of Tanks, it refers to the biggest and most explosive slowly reloading gun that one can have for a particular tank.
Hey, do you have derp on that KV tank? No, I have the stock gun. Noob.
by SiemaUSA October 15, 2011
The action of pure randomness and retardation.
Guy 1: My entire family just died!!!!
Guy 2:..........derp!
by itzadolfin!! May 10, 2011
An incurable disease, at least until the introduction of Duck Sauce's "Barbra Streisand" with a combination of yelling "Unf Unf Unf" between two mirrors.
Kindoflike Bloody Mary three times, but this one actually works. 50% of the time.

It is known to afflict a certain Jason Liu's face constantly (See "Jason Liu" for more information)

Commonly associated with "Herp"
DocMo: "Hi what's your name?"
Jason: "Derp"
DocMo: "Barbra Streisand"
Kenja: "UNFUNFUNF"
by kendaninjabinja May 02, 2011
The only word that can cause world peace if used correctly. Only chuck norris knows the correct gesture and accent that will cause this to happen.
hey, your that guy who beat my wife at the bar last night! why did you do that!?" "uhh... herp de derp!"
by RageToast October 23, 2010

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