To have a retarded face, or expression causing others to find it funny, creepy or just plain stupid.
Ex. 1 Jennifer Lawrence is the queen of derp because of the faces she makes.

Ex. 2 "I'm bored."
"Me too."
*Awkward silence.*
"Derp."
"Yeah..."

Ex. 3 Jennifer Lawrence Queen of Derp trended on Twitter worldwide. (FACT)
by Swim-on-and-on-and-on.... September 07, 2012
a word to say in place of other words. can be used as any part of speech. it is usually used as an interjection.
guy 1: Aw dude! i blew myself up in minecraft!
guy 2: haha derp!
guy 1: shut up your a derp garrett
guy 2:well your more derpy than anyone i know!
by mwahahaiwillruletheworld December 13, 2011
derp-Interjection

Used when replying to a previous statement that is either 1)irrelevant, 2)unintelligible or 3)pointless.
1) following a conversation that had revolved around riced out cars, Jim adds:
"Does anyone else think that corn dogs looks like rats having sex?"
-DERP!

Jim after smoking weed:

"I woke up, or was I already awake? It doesn't matter because THE CAT WAS STILL sleeping!!! ISN'T that odd?
-DERP

3)The sun hurts eyes!
-DERP!
by DFreshalot September 28, 2011
a stupid person, or action
"Danny, your being a huge derp right now.
by MrSexy282 May 21, 2010
Universal word that can mean anything.
"That was derping awesome"

"Teach me how to derp, teach me-teach me how to derp"

"Go derp yourself you derping piece of derp!"

"Derp you!!"
by JvMarsh November 20, 2011
From the Online multi-player game, World of Tanks, it refers to the biggest and most explosive slowly reloading gun that one can have for a particular tank.
Hey, do you have derp on that KV tank? No, I have the stock gun. Noob.
by SiemaUSA October 15, 2011
The universal replacement for any words.
"dude, stop being such a baby" - "dude, stop being such a derp"

"you've got to be f**king kidding me!" - "you've got to be derping kidding me!"

"did you end up going to the party last night?" - "did you end go going to the derp last d'dd?"
by Derpady Derp August 30, 2011
The action of pure randomness and retardation.
Guy 1: My entire family just died!!!!
Guy 2:..........derp!
by itzadolfin!! May 10, 2011

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