d.p.u.s--Dark Piece of Uncircumsized Skin
ew, why does sumaiya look so much like d.p.u.s? Thats worse then w.p.u.s
by Chelsea! January 22, 2006

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Top Definition
DPU
Don't pop up
"I'm going to sleep, dpu"
by Rugbychick4490 February 20, 2017

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DPU
DPU, or Digital Production Unit, is an employee that works on the digital wing of an advertising company, responsible for the production of as many items as humanly possible.
that geezer is a hard worker. he's got his particularities, but he's an excellent DPU.
by schande May 14, 2007

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