Top Definition
1. A total and complete pwning, the utter destruction and dismantling of someone's pretensions, in the manner of Vincent D'Onofrio from Law and Order

2. A powerful female orgasm
Wow, Vinnie really gave that guy a thorough d'onofing.

When Sue saw what was on Vincent's computer screen, she experienced the most powerful d'onofing of her life.
by droazen March 03, 2005

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