A play of words on "Creme de la creme" meaning "Cream of the cream", this quite literally means "Cream of the shit", for use in describing the worst of the worst of the worst, as invented by a bored French Student one day.
"I'm going to drop all hell on Marketing, I need you to find the "Creme de la merde" of your office to send over there, okay?"
by Peter O'Connor June 12, 2007
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The best of the worst.

(From the French saying, "creme de la creme," except that it means "cream of the shit")
Taco Bell is the creme de la merd of late night fast food dining.
by Anomaly September 25, 2005
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