Top Definition
a soup, usually cream of mushroom or cream of chicken soup, typically used as a fattening agent with rice or noodles in hotdishes.
Mary: "This casserole is delicious! What's in it?"
Joseph: "I use a bag of tatertots and a can of cream of fatass to top it all off."
Mary: "eeww!"
by babyA December 11, 2005
6 Words related to cream of fatass

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