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1. cracked-out
having lost all sense and rationality because of sleep deprivation due to extensive use of meth
tweaker 1: "dude, you look sooo cracked-out."
tweaker 2: "really? i've been up for like 3 days. want a line?"
2. cracked-out
Someone who is tripping, high on drugs, or drunk.
Just look at dat cracked-out bitch.
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