Top Definition
To be high on oxycontin.
Fuck I wish I was cottonballing right now!
by Buffalo Brown December 11, 2006
1 more definition
The act of soaking a cotton ball in any type of alcohol until the cotton ball is saturated. One then places the cotton ball up their butt in order to quicken the effects of being drunk.
Dude, did you see Jeffery last night?
No, Why?
He was cotton balling out of his mind.
by MedMen October 12, 2010

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