When your mouth gets really dry and sometimes sticky from lack of spit. This happens when you smoke weed. So, next time, bring a drink.
"Does anyone have a drink, cause I have major cottonmouth"
by Sarahthay March 22, 2009

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Top Definition
Cotton mouth is not only a very dry mouth from smoking pot, but involves having small bits of mucus and spit, lining mainly the roof of your mouth feeling like cotton when you rub your tounge against it.
"Man I got chronic cotton mouth at the moment."
by Diego August 17, 2003

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term used by teens ; after smoking (usually weed) and you're mouth gets very dry and you get very thirsty
Yo I need a drink, I got the ill cottonmouth.
by anonymous July 04, 2004

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when you smoke pot and your mouth gets dry
by urexcellency May 16, 2003

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occurs after one smokes marijuana; refers to the mouth becoming exceedingly dry, spit becoming sparse and thick, and the roof of the mouth becoming seemingly impossible to reach with your tongue
After smoking the weed Diana found stashed in her dad's apartment, Mel, Grace, and Diana had a bad case of cottonmouth and were desperate to get to Sonic for Route 44 oz. slushes.
by HammyLum March 05, 2009

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When you get a very dry mouth probably from smoking any number of items or not drinking anything in ages.
Yo Reg, gimme another beer I'm gettin' cotton mouth.
by Kevin July 25, 2004

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xerostomia, dryness of the mouth
I had major a terrible case of cotton mouth from sweating all day.
by The Return of Light Joker September 19, 2008

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