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4.
A nicer way of saying a girl is on her menstrual cycle (aka period) while in public.

Also, synonym for period.
Jack: Why is Jill such a bitch today?.
John: Yeah man I heard she was on her comma.

Jack: Wanna have sex when we get home from wally world?
Jill: I can't. I am on my comma today.
Jack: Asswhole.
by Asswhole_with_a_dubya December 14, 2009
 
1.
a very important grammar thang. without it, many sentances would be very different.
with comma: I helped my uncle, jack, off his horse.

without comma: I helped my uncle jack off his horse.
by i do not want any stalkers May 13, 2005
 
2.
A once monthly, twice monthly, bi-weekly, weekly, or daily occurrence in which your boyfriend/male friend/brother becomes completely unbearable.
Alex: God, Chris is being such a bitch about gas money.
Bobbi: He's on his comma.
by KitsuneXKyuubi February 28, 2010
 
3.
According to President George W Bush, a comma is what the US-Iraq war will look like in the history books.
I like to tell people when the final history is written on Iraq, it will look like just a comma because there is -- my point is, there's a strong will for democracy. --George W. Bush
by maffei1- October 05, 2006
 
5.
That tricky situation a girl finds herself in when she's just getting off her period, but isn't exactly "on the market" yet. You know, it might be like day 5 or 6 and a slim pantiliner may be all that is needed. At the same time, no one wants to gross a dude out. It certainly is a quandry. But while PERIODS may stop it right there, COMMAS... are only a pause. There's always more to come after a comma.
Girl #1: Yo Stacy I met this fine brotha at the club last night
Girl #2: That's hot but damn girl, ain't you on your period?
Girl #1: Hell no hunny, that was two days ago! I'm on my comma now.
Girl #2: Well shit, that's a different story then. So what'd you do?
Girl #1: I took him home with me, what else?
by ReiReiK April 16, 2008
 
6.
A rare mix of a camel and a llama, used in Perue as crowd breakers, they are verry powerful spitters
Rev. Al. Sharpten, "If the government had Commas it would have been alot difernt, there not even be any civil rights"
by Palmersurasrex January 28, 2009
 
7.
A period of time where male teenagers experience hormones.
*Kid is bitching to a friend*
Friend: I know you're on your comma, but there is no need to bitch to me.
by Noobyraptor February 12, 2011