To do something that no one has ever done before.
1.Often used when describing having sex with a virgin girl.
John: "Yo i heard you got with that abstinent girl over the weekend, is that shit true?"
Phil: "Yeah man, i was straight columbusing that bittie!"
Bob: "Dude you know that hot but like really conservative girl that says she's saving it for marriage?"
Jim: "Yeah what about her"
Bob: "Saving it for marriage my ass, i just columbused that shit."
Colubumsing (v.)- The act of taking over property which does not belong to you.
My friend's brother is away at boarding school, so she's sleeping in his room now without his permission. She's totally columbusing it, dude!