A medical excuse to anally rape an individual while simulaneously searching for problems with the digestive tract.
Tom's colonoscopy revealed he had a cyst in his small intestine.
by Thillbilli November 20, 2005

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Top Definition
The science of sticking a camera in the anus to find problems withing the digestive system.
Did your family go for their colonoscopy portraits at Wal-Mart yet?
by Ricky Lambert November 22, 2004

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The over-use of smilies, often as an entire message in an SMS or instant messaging. The reason for the word being called "Colonoscopy" is that most smilies utilise the colon symbol ":".
Perry: What do you think of that movie?
Timothy: :) :/ :( :P :S :D
Perry: Stop that colonoscopy, fool!
by Lord Aexerus February 07, 2011

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Smooth, soft, slim fit American Apparel shirt. Custom printed. 100% fine jersey cotton, except for heather grey (90% cotton).

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