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2.
A rather neglected and poor street in Denver,CO. Near East High and City Park.
On this street, there is no absence of drugs and prostitution. There is also an excess of the homeless and fast food resturants.
Need a Ho? Go to Colfax Ave.!
by Scott S. April 12, 2004
 
1.
A very long avenue in the Denver Metro area in Colorado. Most of East Colfax has prostitutes, drugs, gangs, etc., while most of West Colfax is closer to an ordinary, middle-class street (with the exception of the area of W. Colfax in LoDo, which is rather upper-class).
"I be from da Eas Co-fax, yo!"
"My Daddy bought me a loft on Colfax in LoDo!"
by Exirth May 10, 2006
 
3.
Noun.

The Red Light District of Denver, known throughout the city as the street where prostitutes gather. Also, the longest street in America, reaching from Golden through Denver into parts unknown east of Aurora.
"That stupid tart Carrie probably works on Colfax"
by frank carter May 14, 2005
 
4.
A small drinking town with a railroad problem.

That one stop between Auburn and Tahoe
"Where do you live?"
"Colfax"
"Dude that sucks!"
by smalltownho February 13, 2013
 
5.
A town 15 minutes north of Auburn, CA, located between Applegate and Alta. Colfax is known for it's small population (roughly 2,000) and small businesses. Colfax originally formed due to necessity to store cargo from the railroad that now runs through the small town. Now Colfax is known as a stop for people visiting Tahoe or going skiing in the mountains due to the Starbucks and multiple gas stations.

Colfax is surrounded by forestry and natural vegetation, giving other individuals the impression that many of the Colfax youth are druggies.
"I went skiing up in Boreal and had to make a pit stop in Colfax."
by mrmath3 April 11, 2012