1. (adjective) to describe a chick who is very promiscuous, or to put it bluntly she likes gettin her fuck on. (i.e. "That chick's tits are hangin all out her shirt, she's got some serious cheeks in a hoodie)
2. (noun) a fine lookin lady (i.e. "She's got cheeks in a hoodie")
originates from how hot chicks like wearing just a long hoodie with no pants to show off their booty, especially while either preparing for sex or immediately after sex.
When you meet a chick in a club, and you say whats up, and in no time flat, she starts dancing like a slut, then you know she's got cheeks in a hoodie.