This term is usually referres to somebody who is homosexual. They are really good at giving men blowjobs this is similar to the word Cedillo but in a homosexual way. Male prostitutes may sometimes be referred to as Pichardo-Cedillo.
"Cirillo to the Bone" is a phrase used to mock one's overall intelligence and skills. Another variation of this phrase is "Boned to the Cirillo" which essentially means that someone is screwed, or in deep shit.