While the term is ordinarily used in a sexist manner to insult a woman's beauty, cankles may represent more than a mere cosmetic problem, but actually a dangerous situation calling for evfaluation by a physician.
It is the condition where the ankle girth is equal to or indiscernibly less than the girth of the widest part of the calf. It is not ankle fat per se, but rather a state of being “big-boned” in the ankle region while simultaneously experiencing gross muscle atrophy of the gastrocnemius.
Symptoms include: deep elastic grooves from socks, increased razor wear-and-tear, ability to reap 20 bushels of grain per hour.
Man 2: "Hopefully she'll marry a farmer"