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Cankerous 

A slut, typically a dirty prostitute or meth whore, exhibiting a variety of infected pustules around the mouth, genitala ans rectum including, but not limited to herpes, cold sores, genital warts and scabies.
Roger stopped to pick up a prostitute for a blow on the way home but the street walkers out that night were way to Cankerous so he just went home and gave it a wank.
Cankerous by Eaton Holgoode November 28, 2015
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Crotch Cankers 

Sores around the genitals or the anus. Generally, reflective of a filthy, disease ridden individual and of the STD variety. However, may apply to non-STD sores like a good old fashioned fuckburn sore or other skin irritation.
Dude I couldn’t get out of the hotel room fast enough after that dirty whore dropped her panties and revealed a gold mine of crotch cankers.

She told me she has a few crotch cankers around her anus before I went down on her and ate that booty. She said they were just fuckburns from the dude she was with the day before.

I need to get to the doctor. I hooked up with Rachel last night. I was warned she had crotch cankers but didn’t sheath up. Now my balls are on fire and it stings when I pee.
Crotch Cankers by Eaton Holgoode February 14, 2018

cankersaurus rex

Similar to a canker or a canker sore, a cankersaurus rex is incredibly painful and occurs in the most inconvenient areas of one's mouth.
I woke up this morning with a wicked canker sore on the tip of my tongue... but I accidentally chomped it midway through a delicious bite of Oreo O's. Now it's definitely a cankersaurus rex. Brutal.
cankersaurus rex by c-davidson August 27, 2008

crank cankers

Herpes: Sores shared on your crank. FUN FOR EVERYONE!
Bitch gave me crank cankers!

Your mother is a cankerous whore

Jack Blade quote from Tropic Thunder. His character was experiencing withdrawl from cocaine and he was tied to a tree. Crazy shit ensued.

Basically, It means your mother sleeps with everyone and has deseases between her legs, and most likely, you are unwanted crotchspawn.
"Your mother is a cankerous whore!"
"Damn."
"Hey, remember that time I called your mother a cankerous whore? I didn't mean it man, she's a nice lady." - Tropic Thunder

Cankerslutt

A man who doesn't know what or when he is going to pass it onto you.
A cankerslutt sneaks up on you like a canker sore.
Cankerslutt by JaneTrader February 12, 2023

Cankersnitchle 

A goofy, endearing nickname for someone. Can be used lovingly (“my little cankersnitchle”) or teasingly, like calling someone a gremlin.
“It’s ok, my little cankersnitchle.”

“Don’t be such a cankersnitchle, share the fries.”

“She calls him cankersnitchle, so you know he’s whipped.”
Cankersnitchle by ChellyCookieArt August 30, 2025