It means an awkward or inept way of doing something; originally meaning left handed, stemming from cultures that use their right hand to eat and their left hand to wipe their behind.
by The Acid Drop Kid October 19, 2007
Someone who is cackhanded is lefthanded, and hence a clumsy fool who can't write or use a knife and fork properly.
My sister is cackhanded. It's really annoying because you can never find righthanded scissors in the house despite the fact that 3/4 of my family are righthanded. I'm sure she chucks them away as a result of her bitter twisted resentment of the fact she's not normal.
by RH Rule August 15, 2006