It came from killer instinct in which you could stop someones combo right then and there hense why it is called a combo breaker which the announcer pronounces it C-C-C-C-Combo Breaker
Play KI you shall see
In a message board, when someone breaks a chain of people repeating the same phrase, it is considered a c-c-c-combo breaker.
In a topic on a message board...
n00b102: What is Doom?
1337Guy: It's a computer game.
nubkiller: It's a computer game.
sexigurl: It's a computer game.
1337one: It's a game from id software.
It's an expression to say that someone changed something that had been repeated.
A bunch of white US presidents until Barack Obama broke repeated combo.