to have a good time; party
"Let's all go over to Jake's house party and bust it up with the honeys there!"
by nitro February 03, 2004
smash an ecstacy pill to parachute or snort it
Gimme a pill man I'm gonna bust it up and rail it.
by mr. nice guy February 17, 2005
talk for a long time
me and the jawn bust it up. Now i know I errythin about her.
by Anonymous October 08, 2003