n.: (American slang) the genital area; can be used for both males and females.
"I have a date with Mr. Wonderful tonight, and should therefore shave my business district."
by Emmy Foofoo May 4, 2008
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noun; euphemism for one's crotch or the human genitals, including but not restricted to balls, cock, cojones, dick, stones or woody in men, or cunt or pussy in women
"Gotta protect the ol' central business district," I sighed as I pulled on my jock strap before going out on the field.
by bongoman October 18, 2007
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A males crotch / groin area.
Why isn't Derek playing short-stop?

"He was, but then a ground ball bounced up and hit him in the 'downtown business district' -- if you know what I mean -- and he had to come out of the game."

OUCH!
by mike87111 November 22, 2013
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