A heroine addict; junkie.
That bupo looks extra strung out.
by Krotch Hammer August 25, 2010
1 more definition
B.ig U.gly P.iece O.f S.hit
"Get that bupos out of my way!" (Used frequently to politely swear at huge SUVS, trucks, motorhomes and other assorted motorized monstrosities lumbering along slowly in front of you in traffic!)
by Starwatcher September 08, 2006