Fucking something up extremely, or not being able to focus.
Usually being said if something bad happens while under the influence of some kind of drug.
"Don't be buffalo, do bomb."
"James, you buffalo you broke my front door?!"
"Your being buffalo."
by Nic M. December 28, 2007
A derogitory term for someone of flemish (belgium) decent.
That buffalo makes good waffles
by Vincent June 03, 2004
"dude, that guy just totally buffaloed you!"
by NO50 November 03, 2003
take a dump
"5- i gotta buffalo"
by lauren September 01, 2003
a hipster filled city
was once a great place to live, and now is pretty much the ghetto.
is filled with skaters.
isn't a great place to live
and is known for the sabers, bills, drugies, drunkies, and buffalo wings
buffalo is filled with drunk, druged up, hipster sports fans.
by madelinekathryn May 14, 2008
A city in western New York which thinks it has a lot going for it because they have a NFL team but it's really as big a %&^%hole as everywhere else in Western NY. Plagued by abandon buildings and run down neighborhoods, Buffalo is not a place anyone should be proud to call home.

While Buffalo is a urban area, it is mostly full of drunk rednecks who are obnoxious and loud. You would think it was a small city in Georgia.
You went to Buffalo, NY? I'm so sorry
by Nancy1198 January 21, 2007
A small city far upstate. Depressed, crime-ridden and boring; could probably turn itself around if it tried to be New York City instead of Detroit.
Upstater: "There's more to New York State than New York City."

Everyone else: "Nobody cares."
by NYC > Buffalo May 24, 2004
The shit-hole capitol of the east.
That dog just dropped a huge buffalo.
by Cuse4Lyfe November 05, 2003

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