Condition of sulfurus and spicy ass-fumes as a direct result of eating foods seasoned with buffalo sauce.
Those wings were amazing, but I can feel a case of buffalo butt coming on!
by KillerR0b0T June 25, 2010
1 more definition
the incredibly huge buttocks of a woman(usually black).
"my god! Linda Burl has the biggest buffalo butt in the whole fucking world!"
by whitey April 08, 2003