The male version of camel toe.
Dude, his buffalo knuckle is too much for me to bare!
by andersonland.org November 15, 2004
Cameltoe, deerfoot, major labia, pussy lips, & pek-pek(pinoy)
Ay dog, you see the buffalo knuckle on that breezy!!!
by N E 1 4 A 69' September 01, 2006