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1.
-to put your guy friends above female friends and even your girlfriend. This means; No ditching, flaking, snitching, or trying to steal his girlfriend.
Guy - Dude, are you coming to the game with us?
Other Guy - I can't, I'm taking my girlfriend shopping
Guy - Bros b4 Hoes
Other Guy - Ok, I'll call her and cancel

-or-

Guy - I was completely wasted last night and cheated on my girlfriend
Other Guy - Dude, not cool. I'm gonna tell her
Guy - C'mon, Bros b4 Hoes
Other Guy - Or I won't tell her
by Gangsta Gangsta December 26, 2006
 
2.
Male friends are more important than stupid female friends.
James's girlfriend wanted him to go to the movies with her, but James´s male friends told him "bros b4 hos!" and James went to the bar for drinking with his male buddies
by niggapleasemore October 04, 2008