To abuse any licit or illicit substance via insertion into one's rectum.
Dude, I just saw Brian boofing some booze last night at a party. Rad!
by Beans n rice October 21, 2013
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Honestly, I don't know what it means but some kid in my Italian class keeps on threatening to do it to the teacher
Gerry wants to boof Signor Vita
by Bitcharoux April 6, 2019
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To insert your drug of choice into your rectum to take advantage of the higher absorption rates found there as opposed to the stomach. Typically done with pills and liquids.
Person 1: You ever boofed a roll?
Person 2: I'm a nasty motherfucker.
Person 1: Nuff said.
by RyanFNation September 25, 2018
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Something of low quality, something very unappealing, or a situation that isn't very fair.
a. "This video game I just bought is so boof, dude."

b. "I would go to that concert, but it looks like it's going to be pretty boof."

c. "My whole day has been boof."
by FRZYKA1 March 1, 2012
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A knock off item, or an illegitimate imitation of a name brand item, most commonly used with designer clothes or jewelry.
“That Chinese website isn’t selling legitimate jerseys, they’re all boof jerseys.”

“I got a boof Rolex for only $30.”
by Tyrondre February 20, 2020
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Strong ass Weed, the type of shit that knocks you on your ass
I don't want friends, I want Audis (what?)
Smokin' on boof and it's Maui (ayy)
-Smokepurpp
by #253 October 11, 2018
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Smelled dat boof got me feinin
by iamSWISH November 9, 2014
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