To smoke an entire eighth of marijuana in one sitting, usually one blunt. If you're hood, you'll burn this 50 in an oowop
. Also the title of a Nas
track off his album, "The Lost Tapes."
"Yo, round up the homies.I just copped some o.g. Let's blaze a 50 and get straight stupid."
"Blaze a 50, sit back in the drop top Azure Bentley. Of course wit me, this chick who'd make Bobby divorce Whitney." - Nas