When you are smoking some marijuana and you think you start to feel a little high, it is that intense high feeling you get right after you take one more hit that takes you to fucking space.
"Dude I just got a little high" *takes one more hit* *1 second later* "Hoooolllyyy shhhiitttt duuude, BLASTOFF!."
by Dennis V Blastoff March 09, 2010
Top Definition
Taking a hit of DMT (Dimethyltryptamine), as this will be your rocket ship to the moon!
It's been a long night, time to blast off and watch the sunrise.
by pocketfrog April 15, 2011
The act of smoking marijuana while you are tripping on acid.
(guy) Yo you want to smoke a blunt?

(guy2) Nah man im trippin balls

(guy1) I know but i wanna blast off!
by Lucidreamer February 16, 2011
The act of cumming on a woman.
I had a hard blast off in her face after that mic check!
by Duke February 24, 2004
an expression ofen used by youth in place of outdated terms such as "cool" or "bitchin'."
Dude! That dunk was totally blastoff!!!!
by Will "Blastoff" C. February 05, 2007
Reaching the pinnacle of creative expression in one's chosen endeavor. Sort of like how we identify Neo in The Matrix.
Dan was so inspired to paint something that he blasted off on the canvas with every idea that came to mind.

Mike was so desperate to get on the other side of the river that he had to blast off in one magnificent leap.
by Balfdor October 11, 2006
To cum vigorously and copiously.
Thinking about Rena really makes me blast off!
by pentozali November 06, 2011

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