look up any word, like fleek:
 
1.
Originally a Dr. Dre song, but has since evolved into a generic saying used to blow off a shitty situation involoving a female. The song has since been remade by Ben Folds.
Guy: Dude, I broke up with Anna last night.

Friends: Screw her dude, bitches aint shit, lets get wasted.
by peaceoutmaw December 08, 2006
 
2.
when girls piss you off, you get mad
Andrew: That bitch never called me back
Bret: man, bitches aint shit
by bretwags April 23, 2008
 
3.
Self explanatory. Bitches(as in ho's and sluts and ugly cuntfaces) ain't(are not) shit(nothing good. stupid. smelly. ugly.
Dooby: dude wtf. girls hate me. im gonna go to mexico when no one is looking!
jeff: Bitches ain't Shit!
Dooby: :( i am robo dooby. i have no emotion.
by jeffwebb November 20, 2005