An extremely large bomb, often nuclear.
During the Cold War the United States was afraid that the Soviets would drop the big one.
by blenheimears April 14, 2009
one thousand dollars
I just bet two big ones on black jack.
by Teemuh April 30, 2008
a pleasantly large penis
I think my cervix is dented ... he has a BIGONE!
by carefulgirl September 12, 2006