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1.
To completely dumbfound, confuse, or otherwise render speechless by either asking a question or stating something beyond their intelligence.
Toni:The mechanism of endocannabinoid synaptic transmission is believed to occur as follows: first, transmission of the excitatory neurotransmitter glutamate causes an influx of calcium ions into the post-synaptic neuron.

Guy: ummm... what? (Toni baffled Guy)
by WhtRhino October 07, 2008
 
2.
To rub one's balls on their friend's waffle
Hey Ash, how does That baffle taste?

WTF
by Smashley02129 December 20, 2013
 
3.
Bitch.ass.fucker.fucking.lonely.elephants
Man you are such a baffle!
by Killa Ki. July 15, 2008
 
4.
alcoholic hermit, homosexual character, approach with extreme care he is armed with a vb tinnie
i went out last night and got baffled
by Anonymous June 27, 2003
 
5.
another way of saying "werd"
one person: I got high last night.
another person: baffle
by Sar February 15, 2004