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1.
An eye condition that usually requires glasses in order to cope with. Usually causes bad eyesight up to and including legal blindness.
My astigmatism is a difficult affliction.
by Christian Cruz November 22, 2006
 
2.
makes your eye turn gay in 2 days
"Stop looking at my butt with that astigmatism eye!"
by Kaven Grenade August 23, 2004