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A derrogatory term used to refer to one who is like an anal itch that you can't quite get rid of. More directly, it compares an extremely annoying person (usually a pestering co-worker) to a small burrowing insect that has made its home up your ass.

The term itself was most famously coined in a fit of rage by one Mat Noguchi, the notoriously hostile tools developer for Bungie Studios (creators of the Halo video game franchise).
Bill (for the millionth time): "Hey Nick, do you have those reports ready for me yet?"

Nick: "GODDAMMIT BILL! FOR THE MILLIONTH FUCKING TIME I WON'T HAVE THE REPORT DONE TILL FRIDAY! GOD YOU ARE SUCH AN ASS-WEEVIL!!! I HOPE YOU DIE!"
by Mr. Horsefly April 11, 2006
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