The politically correct way of describing something as "negatively gay," also meaning, but not limited to:
3. not Karta;
4. going against all things that are cool;
5. going against all the teachings of Kooch.
Anti-heterosexualism may be used to describe diseases, but it is not advised.
If your reaction to "curing a ham" is "OMG you guys the ham is sick?" then you may be anti-heterosexual.
"That shirt he is wearing is very anti-heterosexual."
"I can't believe she's dating her. That's seriously anti-heterosexual."