A progressive, terminal disease where one's motor neurons degrade. This causes muscle weakness and atrophy and eventually death. Also known as Lou Gehrig's Disease.
"He died of amyotrophic lateral sclerosis."
by Samantha Wilson April 30, 2007
Top Definition
A huge ass name for ALS.
He has amyotrophic lateral sclerosis - Dan
The fuck is that? - John
ALS - Dan
Oh -John
by x crackersmacker x March 01, 2010

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