Top Definition
Being able to use a computer mouse efficiently with either the left hand or the right hand.
I wish I was ambimousetrous like you Roberta.
by Roberta Cromer August 18, 2007
1 more definition
Being able to use a computer mouse with either hand.
Frank from I.T. caught all the girls' eyes at the library's computer lab with his ambimousetrous skillz.
by Sun Wolf August 07, 2011

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