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2.
another way of saying,"How ironic!"
Dude: Man, I saved up $50,000 for that new plama, only to find out that they don't sell it anymore.

Chick: Ain't that a bitch!
by Spontania April 27, 2008
 
1.
According to Chris Rock, this is what you would say if you were an organ donor, died, were brought back to life, and no longer had any eyes.
Chris: "Momma, where my eyes at?"
Mom: "Well, honey, you died so we gave them to a kid in Rwanda"
Chris: "Aint that a bitch."
by Flight23 August 08, 2006
 
3.
a comment describing something as "sucking" or being bad
Zac: yo i gotta vagina and a dick dude

Grant: aint that a bitch
by G Will November 22, 2004