Top Definition
That great feeling you get after sex. Some of the cures include: cold pizza, a nice glass of water, and of course, cuddling.
Cindy: "Hey, wanna go out and see a movie?"
Jill: "No thanks, I just got back from my boyfriend's house, and I have major aftersex-itis. Frankly, I don't want to move."
by Pelican Paulie April 24, 2007

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